Generic Name:

Nirmatrelvir and Ritonavir

Paxlovid (nirmatrelvir tablets co-packaged with ritonavir tablets) has a Emergency Use Authorisation (EUA) from the FDA to treat mild-to-moderate COVID-19 in adults and children who have a current diagnosis of mild-to-moderate COVID-19 and are at high risk for progression to severe COVID-19, including hospitalization or death. Patients must be 12 years of age and older weighing at least 88 pounds (40 kg).

Paxlovid should be taken as soon as possible after diagnosis of COVID-19. It is taken to decrease the number and severity of symptoms or avoid severe illness which may lead to hospitalization or death.


For investigational use only

Nirmatrelvir: 300 mg orally twice a day
Ritonavir: 100 mg orally twice a day

Duration of therapy: 5 days

Precaution & Warnings:
Possible side effects of Paxlovid are:

Liver Problems. Tell your healthcare provider right away if you have any of these signs and symptoms of liver problems: loss of appetite, yellowing of your skin and the whites of eyes (jaundice), dark-colored urine, pale colored stools and itchy skin, stomach area (abdominal) pain.
Resistance to HIV Medicines. If you have untreated HIV infection, Paxlovid may lead to some HIV medicines not working as well in the future.

Prescription Information:
Proper doctor prescription is needed.
*Note: The prescription should not be older than 6 month.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Some medicines may interact with Paxlovid and may cause serious side effects. Keep a list of your medicines to show your healthcare provider and pharmacist when you get a new medicine.

You can ask your healthcare provider or pharmacist for a list of medicines that interact with Paxlovid. Do not start taking a new medicine without telling your healthcare provider. Your healthcare provider can tell you if it is safe to take Paxlovid with other medicines.

Tell your healthcare provider if you are taking combined hormonal contraceptive. Paxlovid may affect how your birth control pills work. Females who are able to become pregnant should use another effective alternative form of contraception or an additional barrier method of contraception. Talk to your healthcare provider if you have any questions about contraceptive methods that might be right for you.

Do not take Paxlovid if you are taking any of the following medicines:

pethidine, piroxicam, propoxyphene
amiodarone, dronedarone, flecainide, propafenone, quinidine
lurasidone, pimozide, clozapine
dihydroergotamine, ergotamine, methylergonovine
lovastatin, simvastatin
sildenafil (Revatio®) for pulmonary arterial hypertension (PAH)
triazolam, oral midazolam
carbamazepine, phenobarbital, phenytoin
St. John’s Wort (hypericum perforatum)
Taking Paxlovid with these medicines may cause serious or life-threatening side effects or affect how Paxlovid works.

These are not the only medicines that may cause serious side effects if taken with Paxlovid. Paxlovid may increase or decrease the levels of multiple other medicines. It is very important to tell your healthcare provider about all of the medicines you are taking because additional laboratory tests or changes in the dose of your other medicines may be necessary while you are taking Paxlovid. Your healthcare provider may also tell you about specific symptoms to watch out for that may indicate that you need to stop or decrease the dose of some of your other medicines.


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