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Pacemaker Implantation

“Overview

A pacemaker is a small device that can be used to regulate the heartbeat by implanting it into the chest of the patient. It is an electrical device and sends electrical impulses to the heart muscle to maintain a suitable rhythm and heart rate. In dual-chamber pacemakers, two-leads are implanted in the heart. One lead paces the ventricle and one paces the atrium. It closely matches the natural pacing of the heart.

Types of pacemaker

Pacemakers are of three types:

Single chamber pacemaker: Single chamber pacemaker usually carries electrical impulses from the pulse generator to the right ventricle of a heart.
Dual-chamber pacemaker: A dual-chamber pacemaker carries electrical impulses from the pulse generator to both the right atrium and right ventricle of your heart.
Biventricular pacemaker: A biventricular pacemaker stimulates both lower chambers of the heart (the left and the right ventricles) to make the heartbeat more efficiently.
Indications for Pacemaker Implantation

A specialist may consider the pacemaker placement necessary when medications and other less-invasive procedures do not work effectively at correcting heart problems. Some of the conditions that may involve the implantation of a pacemaker are:

Bradycardia: Bradycardia is the condition in which the heart beats too slowly, causing symptoms such as dizziness, fatigue, or fainting spells.
Atrial fibrillation: It is a common heart rhythm disorder in which the upper chambers of the heart beat chaotically and rapidly. Medicines that are used to control atrial fibrillation may result in slow rhythms that can be treated by the pacemaker.
Congestive Heart failure: Congestive heart failure is a condition in which the heartbeat is not sufficient to supply a normal volume of oxygen and blood. A pacemaker can be carefully implanted to increase the force of muscle contractions in the heart.
Syncope (Frequent fainting spells): A pacemaker may be used to prevent the heart rate from slowing down to the point of fainting.
A dual-chamber pacemaker is necessary to the implant when the heart is too weak to maintain the timing of the right ventricle and atrium.
Tests and diagnosis

Medical history and Examination: The consultant evaluates the complete medical history of the patients and performs a clinical examination.
Following Imaging Tests are done:

Electrocardiogram
Echocardiogram: ECG shows the functioning of the heart, and recorded pictures allow the doctor to measure the thickness and size of the heart muscle.
Holter monitoring: It records the heart rhythms of the patient for an entire period of 24 hours.
Stress test
Pacemaker Implantation Procedure

Before Procedure

The cardiologist discusses the procedure with the patient in detail.
The patient must inform the doctor about the past and present medical problems and previous operations if any.
Preoperative assessment of the patient is done to check the fitness for surgery.
The patient must discuss with a consultant if he/she is allergic to anesthesia.
It is advised to stop certain medications a few days before surgery.
Before the surgery, the doctor advises the patient to stop smoking, exercising regularly and eating a healthy diet.
During Procedure

Pacemaker implantation usually takes about 1 to 2 hours.
A small incision or cut is made in the upper-left side of the chest and the dual-chamber pacemaker is placed just underneath the skin.
With the help of X-ray imaging, the surgeon inserts two wires into the subclavian vein and directs them to their respective chambers in the heart.
The wires are connected to the pacemaker and tested.
The incision is then closed.
After Procedure

The patient is hospitalized for 1-2 days to make sure if the pacemaker is functioning properly.
The patient may feel some discomfort or pain during the first 48 hours of having pacemaker implantation and the patient will be given some pain-relieving medication.
The patient may have some bruising at the place where the pacemaker is inserted. This goes within a few days.
Painkillers and antibiotics are prescribed to fight infection and pain.
Frequent follow-up visits after the first six months of the surgery are important to determine if pacemaker settings are needed to be adjusted.
Lifestyle changes, i.e., maintaining a healthy weight and regular exercise are important for improved prognosis.”

How it works?

1.

Request for medicine

Patient who has serious problem request for medicine

 

2.

Drug Verify

Internal processing of drug verifications at GM Global

 

3.

Prescription

Recognizing best source for the specific prescription

 

4.

GDP Instruction

Import medicine under the GDP instruction

 

5.

QA check

Supply drugs to concerned healthcare provider after QA check

 

5.

QA check

Supply drugs to concerned healthcare provider after QA check

 

FAQ

A NPP provides access to post-approval drugs that are approved and commercially available in one or more country, other than the patient’s home country.

 

No. Companies are not required to provide their products through a formal NPP.

 

  • Dealing with unsolicited patient request for drug in an ethical and regulatory controlled manner
  • Providing exposure to, and experience with, company products to physicians in additional countries and build a larger KOL network and future advocates
  • Providing new products to patients who would move to commercial drug when it becomes available in these countries
  • Generating additional revenues in countries that allow you to charge for drugs supplied on a named patient basis

Companies can provide drug to patients in any country in which they have not yet received marketing approval. This includes countries in which a company plans to seek marketing approval, as well as those countries in which a company does not plan to seek marketing approval.

 
 

INFORMATION FOR PATIENTS

As a named patient medicines you may find yourself in the frightening position that you have a serious condition or illness and the treatment you need is not available in your home country. It is possible that the medicines are available outside your country and if your physician decides that these drugs would be suitable for the treatment of your illness, they then face the challenge of obtaining them for you. We help physicians across the world access medicines which are not approved or licensed in their country, but may be required to meet the special needs of an individual patient. The service we provide not only locates and supplies the required medicines but ensures that the physician has all the quality assurance and supporting clinical information they will need to safely prescribe it to you. If you are confronted with a situation where a drug is not available to you, talk to your physician or healthcare professional about Named Patient Program and ask them to contact us. We will then work directly with your physician to help them in patient access program and understand what options are available.

 

 

Drugs We Provide Under NPS

Drug Directory

Orphan Drugs

1.

Request for medicine

Patient who has serious problem request for medicine

 

2.

Drug Verify

Internal processing of drug verifications at GM Global

 

3.

Prescription

Recognizing best source for the specific prescription

 

4.

GDP Instruction

Import medicine under the GDP instruction

 

5.

QA check

Supply drugs to concerned healthcare provider after QA check

 

5.

QA check

Supply drugs to concerned healthcare provider after QA check

 

FAQ

A NPP provides access to post-approval drugs that are approved and commercially available in one or more country, other than the patient’s home country.

 

No. Companies are not required to provide their products through a formal NPP.

 

  • Dealing with unsolicited patient request for drug in an ethical and regulatory controlled manner
  • Providing exposure to, and experience with, company products to physicians in additional countries and build a larger KOL network and future advocates
  • Providing new products to patients who would move to commercial drug when it becomes available in these countries
  • Generating additional revenues in countries that allow you to charge for drugs supplied on a named patient basis

Companies can provide drug to patients in any country in which they have not yet received marketing approval. This includes countries in which a company plans to seek marketing approval, as well as those countries in which a company does not plan to seek marketing approval.

 
 

INFORMATION FOR PATIENTS

As a named patient medicines you may find yourself in the frightening position that you have a serious condition or illness and the treatment you need is not available in your home country. It is possible that the medicines are available outside your country and if your physician decides that these drugs would be suitable for the treatment of your illness, they then face the challenge of obtaining them for you. We help physicians across the world access medicines which are not approved or licensed in their country, but may be required to meet the special needs of an individual patient. The service we provide not only locates and supplies the required medicines but ensures that the physician has all the quality assurance and supporting clinical information they will need to safely prescribe it to you. If you are confronted with a situation where a drug is not available to you, talk to your physician or healthcare professional about Named Patient Program and ask them to contact us. We will then work directly with your physician to help them in patient access program and understand what options are available.